TUBTOOLS : Développement d'outils d'informations sur les médicaments antituberculeux et évaluation de l'amélioration des connaissances des patients

Details

Supervisors

Elsen, Elodie ; Noirhomme, Séverine ; Carlier, François

Faculty

Faculté de pharmacie et des sciences biomédicales

Degree label

Master de spécialisation en pharmacie hospitalière

Abstract

Introduction: Tuberculosis remains a major public health problem, with 20% of patients experiencing suboptimal treatment adherence. Furthermore, tuberculosis is often poorly understood by healthcare professionals (HPs) working outside of hospital settings. Tools developed by pharmacists could help improve patients’ knowledge about their medications and inform HPs. Objectives: The primary objectives are to develop and validate anti-tuberculosis drug information tools (TUBTOOLS), which include TUBTOOL-Patient (a medication booklet for patients), TUBTOOL-MT (an information sheet for general practitioners) and TUBTOOL-POR (an information sheet for community pharmacists) and to evaluate the effectiveness of the TUBTOOL-Patient in improving patients’ knowledge about their medications. The secondary objectives are to assess patient satisfaction with the TUBTOOL received and to evaluate the reception of TUBTOOLS by HPs and their satisfaction with these tools. Methods: The tools created were validated using a process like the Delphi method. First, a validation questionnaire was distributed to clinical experts and two patient-partner committees to refine the content. Subsequently, focus groups (FGs) were conducted with the same participants to finalize the tools. Items were retained based on majority agreement. Then, two interviews were conducted between the investigator and each patient with TUBTOOL to assess improvement in medication knowledge. Results: The TUBTOOLS were validated during FGs involving 14 experts and 17 patientpartner participants. The final version of the TUBTOOL-Patient contains 14 sections. A consensus was reached for all components of TUBTOOL-MT and TUBTOOL-POR. Among the ten patients included in the study, the TUBTOOL-Patient improved medication knowledge by 29,8 %. Satisfaction with TUBTOOL-Patient was high in 9 out of 10 patients. Among HPs confirming receipt of the sheets, 17 out of 18 people were satisfied with them. Conclusion: The study highlights the usefulness of TUBTOOL-Patient in improving patients’drug knowledge. Appreciated by most patients, this tool could play a crucial role in medication adherence, a major issue in the management of this disease.