Impact de l’informatisation sur la sécurité des médicaments oncologiques injectés à l’hôpital de jour : Etude prospective interventionnelle
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- Background: The administration of injectable anticancer drugs carries a high risk of medication errors due to the complexity of treatment protocols, the toxicity of the drugs, and the vulnerability of the patients. Computerizing prescriptions is a promising strategy to improve the safety of the medication process. At the Ardenne Hospital Center, pre-printed paper prescriptions were replaced by the Coméocare® software in order to enhance the safety of injectable oncology drug prescriptions. Objectives: The primary objective is to evaluate the impact of computerization on the safety of injectable oncology drug prescriptions in a hospital initially using a paper-based system. The secondary objective is to harmonize therapeutic protocols between two hospital sites, while aligning with the latest international oncology guidelines Method: Oncology prescriptions were analyzed to identify and classify all prescription errors by type, comparing the period before and after computerization. Each type of error was then ranked according to its severity level. Results: Computerization of the medication circuit in oncology led to a 91,4% reduction in the prescription error rate, particularly those related to missing data or handwritten mistakes. A significant decrease in moderately to minor harmful errors (grades B and C) was also observed. Conclusion: Computerizing the injectable anticancer drug circuit enhances prescription safety but may introduce new types of errors, requiring continued vigilance from healthcare professionals. This transition involves service reorganization, staff training, and on-site support. Regular updates of protocols in Coméocare® are also essential to sustain long-term benefits.