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Surgical and non-surgical treatment options for chronic exertional compartment syndrome of the leg – A systematic review
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Rauschen_Hannah_29701600Marinx_Bastien_36541500_2019-2020.pdf
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- Background: Chronic Exertional compartment syndrome (CECS) is a muscular overuse injury, usually affecting runners, athletes, or military personnel. The present study aimed to provide a systematic overview of the surgical and conservative treatment effectiveness in lower limb CECS. Method: A systematic literature research, following the PRISMA checklist, was conducted. Three databases, i.e. Embase, Pubmed and Scopus, were screened for articles published from 1990 to 2019. After application of the inclusion criteria, 44 studies were included. The quality of the evidence was measured using an adapted version of the Critical Appraisal Skills Programme (CASP). Results: A total of 1036 original articles were identified. Within the 44 selected articles, 37 concerned surgical fasciotomy or fasciectomy, 6 concerned conservative management in form of gait-retraining and physical therapy and one study evaluated the effect of botulinum toxin injections (BoNT-injections) in the affected compartments. Fifteen studies reported satisfaction rates above 70% in patients treated with fasciotomy. Conservative management showed good, but slightly lower results than surgical treatment. Comparative studies between surgical and conservative treatment demonstrated high risk of selection bias. Overall, literature on treatment of CECS is very heterogenous in terms of both outcomes and population. Conclusion: Fasciotomy is an effective treatment in most patients suffering from CECS of the lower leg. Results of conservative treatment by gait-retraining and of treatment with BoNT-injections are promising. Specifically, gait-retraining may be considered as treatment of choice in military personnel, as in this population fasciotomy appears to be less effective than in athletes. Meanwhile, in an athlete population, where fasciotomy remains the standard treatment for CECS, conservative management in form of gait-retraining should at least be envisioned in patients with post-surgical symptom recurrence. However, further evidence in form of high-quality studies with larger populations is needed in this subject.